Siren, L.L.C.
CIK 2005245
13F filing for Q2 2026・No. 925
- Holdings
- US$4.94B
- Quarter change
- +US$1.33B
- Entries
- 119
- Net bought (estimate)
- +US$363.25M
The quarter change is the holdings' value against the quarter before, price moves included — not what was bought or sold; each institution's page estimates that.
Net bought (estimate)
Each stock's change in shares at the quarter-end price, added up: a new position counts as bought, one sold out as sold, shares held long only. Splits are compared split-adjusted; corporate actions under a new CUSIP are not estimated. An estimate from the filings, not actual trades.
- New 25
- Sold out 10
- Cut 21
- Added 31
- Corporate actions 0
- Unchanged 38
Largest holdings
115 stocks worth US$4.93B, options and bonds left out.
| Stock | This quarter | Shares | Value | Weight |
|---|---|---|---|---|
| Scholar Rock Holding CorpCOM | Cut | 9,575,013 | US$526.63M | 10.69% |
| Kymera Therapeutics IncCOM | Cut | 2,935,830 | US$336.65M | 6.83% |
| Erasca IncCOM | Added | 11,397,781 | US$208.81M | 4.24% |
| Veradermics IncCOMMON STOCK | Added | 1,655,374 | US$203.51M | 4.13% |
| Tango Therapeutics IncCOM | Added | 6,179,364 | US$193.17M | 3.92% |
| RVMDRevolution Medicines IncCOM | Cut | 900,000 | US$168.55M | 3.42% |
| Bicara Therapeutics IncCOM | Cut | 5,602,970 | US$166.35M | 3.38% |
| ARWRArrowhead Pharmaceuticals IncCOM | Added | 1,715,476 | US$139.83M | 2.84% |
| ONCBeOne Medicines AGSPONSORED ADS | Unchanged | 465,000 | US$132.51M | 2.69% |
| Edgewise Therapeutics IncCOM | Cut | 3,184,629 | US$129.39M | 2.63% |
Sign in (free) to see its 50 largest holdings and its trades. Sign in
Filings
The quarter's original 13F filings (SEC).
- 13F-HRFiled August 13, 2026SEC ↗
13F covers long positions in US-listed securities only; the data is SEC's, filed within 45 days of the quarter's end.